Quarterback C.J. Beathard is inactive, which means Nick Mullens will back up Jimmy Garoppolo against the Rams.
Running back Jeff Wilson Jr. has been dealing with a calf injury and is inactive. Offensive lineman Tom Compton is active for the fifth consecutive game. Inactive for the second consecutive game is wide receiver Dante Pettis.
On Saturday, the 49ers activated wide receiver Richie James from injured reserve. He is among the team's active players. Also active are cornerbacks Emmanuel Moseley and Ahkello Witherspoon, as the secondary starts to get healthier.
San Francisco activated defensive lineman Darrion Daniels and wide receiver Kevin White from the team's practice squad. Daniels is inactive while White is active. Both will revert back to the practice squad after the game.
Below are the players who will be inactive for the 49ers:
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